L-alpha-Methylleucine methyl ester

Base Information

Chemical Name:L-alpha-Methylleucine methyl ester
CAS No.:90104-02-2
Molecular Formula:C8H17 N O2
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID60546757
Wikidata:Q82424666
Mol file:90104-02-2.mol

Synonyms:L-alpha-Methylleucine methyl ester;methyl (2S)-2-amino-2,4-dimethylpentanoate;90104-02-2;873924-30-2;Methyl (S)-2-amino-2,4-dimethylpentanoate;L-Leucine, 2-methyl-, methyl ester;Methyl 2-methylleucinate;Methyl 2-methyl-L-leucinate;SCHEMBL4374469;DTXSID60546757;KGYSWVMSQARZEB-QMMMGPOBSA-N;AKOS006346753

Suppliers and Price of L-alpha-Methylleucine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-METHYL 2-AMINO-2,4-DIMETHYLPENTANOATE 95.00%
5MG
$ 499.81

Total 6 raw suppliers

Chemical Property of L-alpha-Methylleucine methyl ester

Chemical Property:

PSA：52.32000
LogP:1.62320
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:159.125928785
Heavy Atom Count:11
Complexity:145

Purity/Quality:

95% ^*data from raw suppliers

(S)-METHYL 2-AMINO-2,4-DIMETHYLPENTANOATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C)(C(=O)OC)N
Isomeric SMILES:CC(C)C[C@@](C)(C(=O)OC)N

Technology Process of L-alpha-Methylleucine methyl ester

There total 5 articles about L-alpha-Methylleucine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 90891-88-6
(2S,5S)-2,5-Diisobutyl-3,6-dimethoxy-2-methyl-2,5-dihydro-pyrazine

: 90104-02-2
(S)-(-)-α-Methylleucine methyl ester

Guidance literature:: With hydrogenchloride; In diethyl ether; for 24h; Ambient temperature;

Reference yield:

: 13022-42-9,77167-62-5,84728-06-3,97187-65-0
L-leucyl-L-leucine methyl ester

: 90104-02-2
(S)-(-)-α-Methylleucine methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: toluene / 20 h / Heating

2: 98 percent / CH₂Cl₂ / 84 h

3: 1.) n-BuLi / 1.) hexane, THF, -70 deg C, 1 h, 2.) -70 deg C, 8 h

4: 82 percent / aq. HCl / diethyl ether / 24 h / Ambient temperature

With hydrogenchloride; n-butyllithium; In diethyl ether; dichloromethane; toluene;

Reference yield:

: 90891-79-5
(3S,6S)-3,6-Diisobutyl-2,5-dimethoxy-3,6-dihydropyrazine

: 90104-02-2
(S)-(-)-α-Methylleucine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) hexane, THF, -70 deg C, 1 h, 2.) -70 deg C, 8 h

2: 82 percent / aq. HCl / diethyl ether / 24 h / Ambient temperature

With hydrogenchloride; n-butyllithium; In diethyl ether;