[α-2H]cyclopentyl phenyl ketone

Base Information

• Chemical Name: [α-2H]cyclopentyl phenyl ketone
• CAS No.: 108516-23-0
• Molecular Formula: C₁₂H₁₄O
• Molecular Weight: 175.235
• Mol file: 108516-23-0.mol

Synonyms:[α-2H]cyclopentyl phenyl ketone

Chemical Property of [α-2H]cyclopentyl phenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of [α-2H]cyclopentyl phenyl ketone

There total 4 articles about [α-2H]cyclopentyl phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[cyclopentylidene(phenyl)methoxy]trimethylsilane (196598-74-0) → phenyl cyclopentyl ketone (5422-88-8) + [α-2H]cyclopentyl phenyl ketone (108516-23-0)

Guidance literature:

[cyclopentylidene(phenyl)methoxy]trimethylsilane; With methyllithium; In diethyl ether; at 20 ℃;

With tert-butyl alcohol-d; In tetrahydrofuran; diethyl ether; at -78 ℃; for 0.5h; Title compound not separated from byproducts;

DOI:10.1002/ejoc.200390103

Reference yield:

cyclopentylidene(phenyl)methyl acetate (408334-63-4) → phenyl cyclopentyl ketone (5422-88-8) + [α-2H]cyclopentyl phenyl ketone (108516-23-0)

Guidance literature:

cyclopentylidene(phenyl)methyl acetate; In diethyl ether; at 20 ℃; for 1h;

With tetradeuterioacetic acid; In tetrahydrofuran; diethyl ether; at -78 ℃; for 0.5h; Title compound not separated from byproducts;

DOI:10.1002/ejoc.200390103

Reference yield:

phenyl cyclopentyl ketone (5422-88-8) → [α-2H]cyclopentyl phenyl ketone (108516-23-0)

Guidance literature:

With water-d2;

DOI:10.1021/ja01602a035

upstream raw materials:

phenyl cyclopentyl ketone

cyclopentylidene(phenyl)methyl acetate

[cyclopentylidene(phenyl)methoxy]trimethylsilane