O₆-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine

Base Information

• Chemical Name: O₆-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine
• CAS No.: 1032327-85-7
• Molecular Formula: C₃₆H₅₇N₅O₆Si₂
• Molecular Weight: 712.049
• Mol file: 1032327-85-7.mol

Synonyms:O₆-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine

Chemical Property of O₆-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of O₆-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine

There total 1 articles about O₆-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

O6-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-O2-tris(dimethylamino)phosphonium-2'-deoxyxanthosine hexafluorophosphate + 4,4-ethylenedioxy-piperidine (177-11-7) → O6-benzyl-3',5'-bis-O-(tert-butyldimethylsilyl)-2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2'-deoxyinosine (1032327-85-7)

Guidance literature:

In 1,2-dimethoxyethane; at 20 - 85 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol8006106

upstream raw materials:

4,4-ethylenedioxy-piperidine