methyl (E)-(3R^,4S^)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Base Information

Chemical Name:methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate
CAS No.:88155-83-3
Molecular Formula:C₁₅H₂₀O₃
Molecular Weight:248.322
Hs Code.:

methyl (E)-(3R<sup>*</sup>,4S<sup>*</sup>)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Synonyms:methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Suppliers and Price of methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

There total 22 articles about methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 88088-56-6,90695-46-8,90695-54-8
(E)-(3R,4S)-4-Methoxy-3-methyl-6-phenyl-hex-5-enoic acid

: 88155-83-3
methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Guidance literature:: In diethyl ether;
DOI:10.1246/cl.1983.1379

Reference yield:

: 88088-54-4,106315-62-2,109864-19-9,109864-32-6
(E)-(3S^*,4R^*)-3-methoxy-4-methyl-1-phenylhexa-1,5-diene

: 88155-83-3
methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 9-BBN, 2.) 15percent aq. NaOH, 30percent aq. H₂O₂ / 1.) THF, from 0 deg C to RT, overnight, 2.) THF, EtOH, 4 h

2: 100 percent / 8 N Jones reagent / acetone / 2 h

With sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; jones reagent; dihydrogen peroxide; In acetone;
DOI:10.1021/jo00228a028

Reference yield:

: 79705-07-0,79705-08-1,88088-46-4,88088-47-5
(3S,4R)-4-Methyl-hex-5-en-1-yn-3-ol

: 88155-83-3
methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / CuI / (Ph₃P)2PdCl₂ / diethylamine / 10 h / 50 °C / Irradiation

2: 80 percent / LiAlH₄ / tetrahydrofuran / 3 h / Heating

3: 80 percent / NaH / tetrahydrofuran / 20 - 25 °C

4: 1.) 9-BBN; 2.) 3N NaOH, 30percent H₂O₂ / 1.) THF, 1.5 h at 0 deg C; 2.) at 5-10 deg C

5: PtO₂, NaHCO₃, O₂ / H₂O / 50 h / 90 - 100 °C

6: 87 percent / diethyl ether

With platinum(IV) oxide; sodium hydroxide; copper(l) iodide; lithium aluminium tetrahydride; 9-borabicyclo[3.3.1]nonane dimer; dihydrogen peroxide; oxygen; sodium hydride; sodium hydrogencarbonate; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; diethyl ether; water; diethylamine;
DOI:10.1016/0040-4020(84)80013-7