- Chemical Name:LIPOPHILIC SEPHADEX
- CAS No.:9041-37-6
- Molecular Formula:C9H8N2O3S
- Molecular Weight:224.23642
- Hs Code.:29400090
- Mol file:9041-37-6.mol
Synonyms:SephadexLH-20 Dextran
Synonyms:SephadexLH-20 Dextran
99% *data from raw suppliers
Sephadex LH-20 *data from reagent suppliers
The research investigates the chemical constituents of the plant Pilea cavaleriei subsp. crenata, aiming to identify and characterize new humulane-type sesquiterpenoids. The study successfully isolated nine new and two known sesquiterpenoids from the plant extracts. The structures of these compounds were elucidated using various spectroscopic techniques, including 1D- and 2D-NMR, HRMS, and X-ray crystallography, combined with chemical conversions. Key chemicals used in the research include ethanol for extraction, petroleum ether and methanol for partitioning, silica gel and Sephadex LH-20 for column chromatography, and LiAlH4 and NaBH4 for chemical transformations. The study discovered an ene reaction during chemical conversions, which could explain the prevalence of allylic hydroperoxide groups in natural products. The findings suggest that the Urticaceae family is a rich source of natural sesquiterpenoids, warranting further investigation.