4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol

Base Information

• Chemical Name: 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol
• CAS No.: 256510-69-7
• Molecular Formula: C₄₈H₆₀O₄S
• Molecular Weight: 733.068
• Mol file: 256510-69-7.mol

Synonyms:4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol

Chemical Property of 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol

There total 2 articles about 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

thiophene (188290-36-0,8014-23-1,25233-34-5) + 3-<3-<3-(5-tert-butylsalicyl)-5-tert-butylsalicyl>-5-tert-butylsalicyl>-5-tert-butyl-2-hydroxybenzyl alcohol (68803-63-4) → 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol (256510-69-7)

Guidance literature:

With toluene-4-sulfonic acid; for 4h; Heating;

DOI:10.3987/COM-99-8692

Reference yield:

2-<3-<3-(5-tert-Butylsalicyl)-5-tert-butylsalicyl>-5-tert-butylsalicyl>-4-tert-butylphenol (992-52-9) → 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol (256510-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 25 percent / NaOH / H₂O; methanol; dioxane / 1.5 h / 50 °C

2: 58 percent / p-TsOH / 4 h / Heating

With sodium hydroxide; toluene-4-sulfonic acid; In 1,4-dioxane; methanol; water; 1: hydroxymethylation / 2: Condensation;

DOI:10.3987/COM-99-8692

Reference yield: 64.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxyphenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol (256510-69-7) → 4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxy-3-(hydroxymethyl)phenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol (340811-02-1)

Guidance literature:

With sodium hydroxide; In methanol; at 50 ℃; for 8h;

DOI:10.1002/jhet.5570380144

upstream raw materials:

thiophene

3-<3-<3-(5-tert-butylsalicyl)-5-tert-butylsalicyl>-5-tert-butylsalicyl>-5-tert-butyl-2-hydroxybenzyl alcohol

2-<3-<3-(5-tert-Butylsalicyl)-5-tert-butylsalicyl>-5-tert-butylsalicyl>-4-tert-butylphenol

Downstream raw materials:

4-tert-butyl-2-((5-(tert-butyl)-3-((5-tert-butyl)-2-hydroxy-3-(hydroxymethyl)phenyl)methyl)-2-hydroxyphenyl)methyl-6-((5-tert-butyl)-2-hydroxy-3-(thienylmethyl)methyl)phenol