4-(2-(diMethylaMino)ethoxy)-3-fluorophenylboronic acid

Base Information

• Chemical Name: 4-(2-(diMethylaMino)ethoxy)-3-fluorophenylboronic acid
• CAS No.: 944279-23-6
• Molecular Formula: C₁₀H₁₅BFNO₃
• Molecular Weight: 227.043
• Mol file: 944279-23-6.mol

Synonyms:3-fluoro-4-(2-dimethylamine-ethoxy)-phenylboronic acid

Chemical Property of 4-(2-(diMethylaMino)ethoxy)-3-fluorophenylboronic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-(2-(Dimethylamino)ethoxy)-3-fluorophenylboronic acid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-(diMethylaMino)ethoxy)-3-fluorophenylboronic acid

There total 1 articles about 4-(2-(diMethylaMino)ethoxy)-3-fluorophenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

[2-(4-bromo-2-fluoro-phenoxy)-ethyl]-dimethyl-amine (944279-21-4) → 3-fluoro-4-(2-dimethylamine-ethoxy)-phenylboronic acid (944279-23-6)

Guidance literature:

[2-(4-bromo-2-fluoro-phenoxy)-ethyl]-dimethyl-amine; With iodine; magnesium; In tetrahydrofuran; for 1h; Heating / reflux;

With Trimethyl borate; In tetrahydrofuran; at -78 ℃;

With hydrogenchloride; In tetrahydrofuran; water; for 0.5h;

upstream raw materials:

[2-(4-bromo-2-fluoro-phenoxy)-ethyl]-dimethyl-amine

Refernces