Morpholine, 4-(2-cyclopenten-1-yl)-

Base Information

• Chemical Name: Morpholine, 4-(2-cyclopenten-1-yl)-
• CAS No.: 6284-13-5
• Molecular Formula: C₉H₁₅NO
• Molecular Weight: 153.224
• Hs Code.: 2934999090
• Mol file: 6284-13-5.mol

Synonyms:1-Morpholino-2-cyclopentene;NSC 7174

Chemical Property of Morpholine, 4-(2-cyclopenten-1-yl)-

Chemical Property:

• Vapor Pressure: 0.107mmHg at 25°C
• Boiling Point: 221.4°C at 760 mmHg
• PKA: 7.42±0.20(Predicted)
• Flash Point: 63.8°C
• PSA: 12.47000
• Density: 1.062g/cm³
• LogP: 0.97510

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Morpholine, 4-(2-cyclopenten-1-yl)-

There total 5 articles about Morpholine, 4-(2-cyclopenten-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

morpholine-4-carboxylic acid cyclopent-2-enyl ester → 3-morpholinocyclopentene (6284-13-5)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In dichloromethane; at 40 ℃;

DOI:10.1055/s-2005-918949

Reference yield:

morpholine (110-91-8,99108-56-2) + 3-acetoxycyclopent-1-ene (20657-21-0) → 3-morpholinocyclopentene (6284-13-5)

Guidance literature:

;

DOI:10.1021/jo00386a004

Reference yield:

morpholine (110-91-8,99108-56-2) + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) → 3-morpholinocyclopentene (6284-13-5) + trans-4-deuterio-3-morpholinocyclopentene (77213-23-1)

Guidance literature:

With tetrakis (triethyl phosphite) nickel; sulfuric acid; Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1016/S0040-4039(00)74545-X

upstream raw materials:

morpholine

3-acetoxycyclopent-1-ene

cyclopenta-1,3-diene

Refernces

• 1、 Fiaud, Jean-Claude,Legros, Jean-Yves. "New Method for the Classification of Nucleophiles in the Palladium-Catalyzed Substitution of Allylic Acetates". . p. 1907 - 1911. Retrieved 2007/10/02.
• 2、 Moberg, Christina. "STEREOCHEMISTRY OF NUCLEOPHILIC ATTACK BY AMINE ON A CATIONIC Π-ALLYLNICKEL COMPLEX". . p. 4539 - 4542. Retrieved 2007/10/02.