2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile

Base Information

• Chemical Name: 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile
• CAS No.: 71945-92-1
• Molecular Formula: C₂₁H₁₃FN₄
• Molecular Weight: 340.359

Synonyms:2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile

Chemical Property of 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile

Chemical Property:

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Technology Process of 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile

There total 4 articles about 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-Amino-6-(4-fluoro-phenyl)-4-phenyl-cyclohexa-2,4-diene-1,1,3-tricarbonitrile (71945-85-2) → 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile (71945-92-1)

Guidance literature:

With potassium hydroxide; for 0.0833333h; Heating;

DOI:10.1007/BF00519529

Reference yield:

(2Z,4E)-2-(1-Amino-2,2-dicyano-vinyl)-5-(4-fluoro-phenyl)-3-phenyl-penta-2,4-dienenitrile (94611-55-9) → 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile (71945-92-1)

Guidance literature:

With diethylamine; In ethanol; for 0.166667h; Heating;

DOI:10.1007/BF00519529

Reference yield:

C21H12FN4(1-)*K(1+) (107487-55-8) → 2-[3-Cyano-6-(4-fluoro-phenyl)-4-phenyl-5,6-dihydro-1H-pyridin-2-ylidene]-malononitrile (71945-92-1)

Guidance literature:

With hydrogenchloride; In ethanol;

DOI:10.1007/BF00519529

upstream raw materials:

2-Amino-6-(4-fluoro-phenyl)-4-phenyl-cyclohexa-2,4-diene-1,1,3-tricarbonitrile

C₂₁H₁₂FN₄^(1-)*K⁽¹⁺⁾

(2Z,4E)-2-(1-Amino-2,2-dicyano-vinyl)-5-(4-fluoro-phenyl)-3-phenyl-penta-2,4-dienenitrile

Downstream raw materials:

C₂₁H₁₂FN₄^(1-)*K⁽¹⁺⁾

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