(1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Base Information

Chemical Name:(1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide
CAS No.:267873-91-6
Molecular Formula:C₂₆H₃₆O₇
Molecular Weight:460.568
Hs Code.:

Synonyms:(1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Suppliers and Price of (1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

There total 15 articles about (1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 66696-81-9
5-(1-hydroxyoctylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

: 267873-90-5
(3S,4R)-3,4-isopropylidene-5-p-methoxybenzyl-1,3,4,5-tetrahydroxy-2-pentanone

: 267873-91-6
(1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Guidance literature:: 5-(1-hydroxyoctylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione; (3S,4R)-3,4-isopropylidene-5-p-methoxybenzyl-1,3,4,5-tetrahydroxy-2-pentanone; In tetrahydrofuran; for 3h; Heating;

With silica gel; In hexane; ethyl acetate; at 20 ℃; for 18h; Further stages.;
DOI:10.1021/jo991989e

Reference yield:

: 3-Oxo-decanoic acid 2-[(4S,5R)-5-(4-methoxy-benzyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-oxo-ethyl ester

: 267873-91-6
(1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Guidance literature:: With silica gel; In hexane; ethyl acetate; at 20 ℃; for 18h;
DOI:10.1139/v99-252

Reference yield:

: 14289-62-4
1-(allyloxymethyl)-4-methoxybenzene

: 267873-91-6
(1'R,2'R)-3-[1',2'-(isopropylidenedioxy)-3'-(p-methoxybenzyloxy)-propyl]-2-octanoyl-2-buten-4-olide

Guidance literature:: Multi-step reaction with 4 steps

1.1: O₃ / CH₂Cl₂ / -78 °C

1.2: 647 mg / Me₂S / CH₂Cl₂ / 3 h / -78 - 20 °C

2.1: FDP aldolase; 1N NaOH / H₂O; dimethylformamide / 72 h / 20 °C / pH 6.8

2.2: 65 percent / 1N HCl; acid phosphatase / H₂O; dimethylformamide / 24 h / 20 °C / pH 4.8

3.1: 67 percent / p-TsOH; 4 Angsteroem MS / 5 h

4.1: tetrahydrofuran / 3 h / Heating

4.2: 71 percent / silica gel / hexane; ethyl acetate / 18 h / 20 °C

With sodium hydroxide; 4 Angsteroem MS; FDP aldolase; toluene-4-sulfonic acid; ozone; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; 1.1: ozonolysis / 1.2: Decomposition / 2.1: Addition / 2.2: Hydrolysis / 3.1: Cyclization / 4.1: Acylation / 4.2: Hydrolysis;
DOI:10.1021/jo991989e