(2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal

Base Information

Chemical Name:(2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal
CAS No.:1383578-57-1
Molecular Formula:C₃₁H₄₃NO₅Si
Molecular Weight:537.772
Hs Code.:

Synonyms:(2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal

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Technology Process of (2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal

There total 1 articles about (2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 649755-76-0
(R)-3-[(2R,3S,4S)-5-hydroxy-2,4-dimethyl-3-(triethylsilanyloxy)pentanoyl]-4-isopropyl-5,5-diphenyloxazolidin-2-one

: 1383578-57-1
(2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal

Guidance literature:: With pyridine-SO₃ complex; triethylamine; In dichloromethane; dimethyl sulfoxide; at 0 ℃; for 3.25h;

Reference yield:

: 1383578-57-1
(2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal

: 94397-40-7
(1-bromoallyl)trimethylsilane

: 1055718-02-9
(R)-3-[(Z)-(2R,3S,4S)-2,4-dimethyl-3-triethylsilanyloxy-octa-5,7-dienoyl]-4-isopropyl-5,5-diphenyl-oxazolidin-2-one

Guidance literature:: (2R,3S,4R)-5-[(R)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl]-2,4-dimethyl-5-oxo-3-triethylsilanyloxy-pentanal; (1-bromoallyl)trimethylsilane; With chromium dichloride; In tetrahydrofuran; tert-butyl methyl ether; at 0 ℃; for 4h; pH=7.0; Aqueous phophate buffer;

With potassium hydride; In tetrahydrofuran; at 0 ℃; for 0.0833333h;