2-Hydroxy-3-nitrobenzenecarbohydrazide

Base Information

• Chemical Name: 2-Hydroxy-3-nitrobenzenecarbohydrazide
• CAS No.: 945-22-2
• Molecular Formula: C7H7 N3 O4
• Molecular Weight: 197.15
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID30463689
• Wikidata: Q82288685
• Mol file: 945-22-2.mol

Synonyms:2-hydroxy-3-nitrobenzenecarbohydrazide;2-hydroxy-3-nitrobenzohydrazide;945-22-2;3-nitrosalicylohydrazide;2-hydroxy-3-nitrobenzhydrazide;SCHEMBL7539226;DTXSID30463689;VOIQCDFMTVQLRZ-UHFFFAOYSA-N;MFCD01930273;AKOS005072489;EB-0820;FT-0680958;A917086;J-509623

Chemical Property of 2-Hydroxy-3-nitrobenzenecarbohydrazide

Chemical Property:

• Melting Point: 206-208°
• Refractive Index: 1.664
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 121.17000
• Density: 1.549g/cm³
• LogP: 1.51830
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 197.04365571
• Heavy Atom Count: 14
• Complexity: 240

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy-3-nitrobenzenecarbohydrazide >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)[N+](=O)[O-])O)C(=O)NN

Technology Process of 2-Hydroxy-3-nitrobenzenecarbohydrazide

There total 2 articles about 2-Hydroxy-3-nitrobenzenecarbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-3-nitro-benzoic acid methyl ester (22621-41-6) → 3-nitro-salicylhydrazide (945-22-2)

Guidance literature:

With sodium hydroxide; hydrazine hydrate; In tetrahydrofuran;

Reference yield:

→ 3-nitro-salicylhydrazide (945-22-2)

Guidance literature:

3-Nitro-salicylsaeure-methylester, N2H4*H2O;

DOI:10.1021/jm00303a006

Reference yield: 88.5%

3-nitro-salicylhydrazide (945-22-2) → bis-(3-nitrosalicylhydrazido)zinc(II) *2HO

Guidance literature:

In methanol; addn. of hot 3-nitro-salicylhydrazide soln. (MeOH) to Zn(II) salt soln. (slightly alkaline by aq. NAc soln.); immediately pptn.; further addn. of 3NSH until supernatant liquid clear; refluxing, 4h; by the method of Amma, Khadikar, Thesis, Vikram, 1980; filtration; washing with methanol and water; drying under vac.; elem. anal.;

upstream raw materials:

2-hydroxy-3-nitro-benzoic acid methyl ester