1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine

Base Information

Chemical Name:1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine
CAS No.:1057676-78-4
Molecular Formula:C₂₅H₂₂F₃N₅
Molecular Weight:449.478
Hs Code.:

Synonyms:1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine

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Technology Process of 1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine

There total 2 articles about 1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.0%

: 40848-53-1
1-benzyl-4-chlorophthalazine

: 132834-58-3
1-[5-(trifluoromethyl)pyridine-2-yl]piperazine

: 1057676-78-4
1-benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]phthalazine

Guidance literature:: With triethylamine; In 1-methyl-pyrrolidin-2-one; at 180 ℃; for 0.5h; Microwave irradiation; Inert atmosphere;
DOI:10.1021/jm900309j