(S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Base Information

Chemical Name:(S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one
CAS No.:1584139-96-7
Molecular Formula:C₁₆H₁₄FN₃O
Molecular Weight:283.305
Hs Code.:

Synonyms:(S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Suppliers and Price of (S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of (S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

There total 11 articles about (S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1584632-62-1
(S)-benzyl (5-(3-fluorophenyl)-9-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamate

: 1584139-96-7
(S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Guidance literature:: With hydrogen bromide; acetic acid; at 20 ℃; for 1h;

Reference yield:

: C₁₆H₁₄FN₃O*C₅H₇NO₃

: 1584139-96-7
(S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Guidance literature:: With sodium hydrogencarbonate; In water; at 25 - 35 ℃; pH=8 - 8.5;

Reference yield:

: 1584632-66-5
benzyl (5-(3-fluorophenyl)-9-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamate

: 1584139-96-7
(S)-3-amino-5-(3-fluorophenyl)-9-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: carbon dioxide / methanol / 45 °C / Resolution of racemate

2: acetic acid; hydrogen bromide / 1 h / 20 °C

With carbon dioxide; hydrogen bromide; acetic acid; In methanol;