(2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid

Base Information

• Chemical Name: (2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid
• CAS No.: 308807-17-2
• Molecular Formula: C₁₄H₂₇NO₄
• Molecular Weight: 273.373
• Mol file: 308807-17-2.mol

Synonyms:(2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid

Chemical Property of (2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid

There total 1 articles about (2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-2,3-dimethyl-2-butene (5072-70-8) → (2S)-2-tert-Butoxycarbonylamino-5,6-dimethylheptanoic acid (308807-17-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Zn; Me₃SiCl / dimethylformamide / 1 h / 20 °C

1.2: 29 percent / CuBr*DMS / dimethylformamide / -15 - 20 °C

2.1: 97 percent / H₂ / 10 percent Pd/C / ethanol / 20 °C

3.1: 100 percent / aq. LiOH / tetrahydrofuran / 20 °C

With lithium hydroxide; chloro-trimethyl-silane; hydrogen; zinc; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

DOI:10.1039/b007032g

upstream raw materials:

1-bromo-2,3-dimethyl-2-butene