(1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Base Information

Chemical Name:(1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester
CAS No.:1013021-54-9
Molecular Formula:C₁₂H₁₉NO₃
Molecular Weight:225.288
Hs Code.:

Synonyms:(1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Suppliers and Price of (1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

There total 3 articles about (1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 152614-57-8
(R)-1-(2-Cyano-ethyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester

: 1013021-54-9
(1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: With sodium tetrahydroborate; In methanol; for 2h;
DOI:10.1016/S0957-4166(00)80054-3

Reference yield:

: 42894-09-7
ethyl 1-(2-cyanoethyl)-2-oxocyclohexanecarboxylate

: 1013021-54-9
(1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: Al(OiPr)3 / propan-2-ol / 3 h

With aluminum isopropoxide; In isopropyl alcohol;
DOI:10.1016/S0957-4166(00)80054-3

Reference yield:

: 152614-57-8
(R)-1-(2-Cyano-ethyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester

: (1R,2R)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

: 1013021-54-9
(1R,2S)-1-(2-Cyano-ethyl)-2-hydroxy-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: With aluminum isopropoxide; In isopropyl alcohol; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/S0957-4166(00)80054-3