benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate

Base Information

• Chemical Name: benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate
• CAS No.: 586952-21-8
• Molecular Formula: C₁₉H₁₉NO₆S
• Molecular Weight: 389.429
• Mol file: 586952-21-8.mol

Synonyms:benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate

Chemical Property of benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate

There total 4 articles about benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

benzyl (E)-4-p-toluenesulfonylaminocarbonyloxy-2-butenoate (586952-15-0) → benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate (586952-21-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 12h;

DOI:10.3987/com-03-9724

Reference yield:

benzyl 3-butenoate (86170-45-8) → benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate (586952-21-8)

Guidance literature:

Multi-step reaction with 4 steps

1: m-chloroperbenzoic acid / CHCl₃ / 5 h / Heating

2: DBU / CH₂Cl₂ / 2 h / 20 °C

3: 92 percent / CH₂Cl₂ / 4 h / 20 °C

4: 78 percent / DBU / CH₂Cl₂ / 12 h / 20 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; chloroform;

DOI:10.3987/com-03-9724

Reference yield:

rac-2-oxiraneacetic acid phenylmethyl ester (110652-75-0,111058-65-2,111058-68-5,111006-13-4) → benzyl (3-p-toluenesulfonyl-1,3-oxazolidin-2-on-4-yl)acetate (586952-21-8)

Guidance literature:

Multi-step reaction with 3 steps

1: DBU / CH₂Cl₂ / 2 h / 20 °C

2: 92 percent / CH₂Cl₂ / 4 h / 20 °C

3: 78 percent / DBU / CH₂Cl₂ / 12 h / 20 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane;

DOI:10.3987/com-03-9724

upstream raw materials:

benzyl (E)-4-p-toluenesulfonylaminocarbonyloxy-2-butenoate

benzyl 3-butenoate

rac-2-oxiraneacetic acid phenylmethyl ester

benzyl (E)-4-hydroxy-2-butenoate