(R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

Base Information

Chemical Name:(R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate
CAS No.:915302-40-8
Molecular Formula:C₁₉H₂₄O₇
Molecular Weight:364.395
Hs Code.:

Synonyms:(R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

Suppliers and Price of (R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

There total 1 articles about (R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6750-04-5
propargyl benzoate

: 503320-97-6
(2R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2-carbaldehyde

: 915302-40-8
(R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

Guidance literature:: With (-)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine; In toluene; at 20 ℃; for 3.5h;
DOI:10.1055/s-2006-947361

Reference yield: 84.0%

: 915302-40-8
(R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

: 915302-48-6
C₁₉H₂₆O₇

Guidance literature:: With quinoline; hydrogen; Lindlar's catalyst; In ethyl acetate; at 20 ℃;
DOI:10.1055/s-2006-947361

Reference yield:

: 915302-40-8
(R,R,R,R)-4-hydroxy-4-(5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)but-2-ynyl benzoate

: 915302-52-2
C₁₉H₂₅NO₁₀S

Guidance literature:: Multi-step reaction with 5 steps

1.1: 84 percent / H₂; quinoline / Lindlar's catalyst / ethyl acetate / 20 °C

2.1: tetrahydrofuran / 20 °C

3.1: 85 percent / LiBr / Pd(OAc)2 / tetrahydrofuran / Heating

4.1: O₃ / CH₂Cl₂ / -78 °C

4.2: Me₂S / CH₂Cl₂

5.1: NaClO₂; H₂O₂; NaH₂PO₄ / acetonitrile; H₂O

With quinoline; sodium chlorite; sodium dihydrogenphosphate; hydrogen; dihydrogen peroxide; ozone; lithium bromide; palladium diacetate; Lindlar's catalyst; In tetrahydrofuran; dichloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1055/s-2006-947361