O₉-(4-vinylbenzoyl)dihydroquinine

Base Information

• Chemical Name: O₉-(4-vinylbenzoyl)dihydroquinine
• CAS No.: 872178-21-7
• Molecular Formula: C₂₉H₃₂N₂O₃
• Molecular Weight: 456.585
• Mol file: 872178-21-7.mol

Synonyms:O₉-(4-vinylbenzoyl)dihydroquinine

Chemical Property of O₉-(4-vinylbenzoyl)dihydroquinine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of O₉-(4-vinylbenzoyl)dihydroquinine

There total 2 articles about O₉-(4-vinylbenzoyl)dihydroquinine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

p-vinylbenzoyl chloride (1565-41-9) + dihydroquinine (522-66-7) → O9-(4-vinylbenzoyl)dihydroquinine (872178-21-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 15h;

DOI:10.1055/s-2004-817781

Reference yield:

4-ethenylbenzoic acid (1075-49-6) → O9-(4-vinylbenzoyl)dihydroquinine (872178-21-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 562.5 mg / thionyl chloride / 1 h / Heating

2: 59 percent / Et₃N / CH₂Cl₂ / 15 h / 20 °C

With thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1055/s-2004-817781

upstream raw materials:

p-vinylbenzoyl chloride

dihydroquinine

4-ethenylbenzoic acid