(7-Chlorothiazolo[5,4-D]pyrimidin-2-YL)isopropylamine

Base Information

• Chemical Name: (7-Chlorothiazolo[5,4-D]pyrimidin-2-YL)isopropylamine
• CAS No.: 871266-86-3
• Molecular Formula: C₈H₉ClN₄S
• Molecular Weight: 228.705
• DSSTox Substance ID: DTXSID20468421
• Wikidata: Q82295609
• Mol file: 871266-86-3.mol

Synonyms:871266-86-3;(7-CHLOROTHIAZOLO[5,4-D]PYRIMIDIN-2-YL)ISOPROPYLAMINE;7-chloro-N-isopropylthiazolo[5,4-d]pyrimidin-2-amine;7-chloro-N-propan-2-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine;DTXSID20468421;BP-20002;CS-0456664;7-Chloro-N-(propan-2-yl)[1,3]thiazolo[5,4-d]pyrimidin-2-amine

Chemical Property of (7-Chlorothiazolo[5,4-D]pyrimidin-2-YL)isopropylamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.694
• Boiling Point: 334.248°C at 760 mmHg
• Flash Point: 155.948°C
• PSA: 78.94000
• Density: 1.452g/cm³
• LogP: 2.63300
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 228.0236452
• Heavy Atom Count: 14
• Complexity: 204

Purity/Quality:

97% ^*data from raw suppliers

(7-Chlorothiazolo[5,4-d]pyrimidin-2-yl)isopropylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)NC1=NC2=C(S1)N=CN=C2Cl

Technology Process of (7-Chlorothiazolo[5,4-D]pyrimidin-2-YL)isopropylamine

There total 1 articles about (7-Chlorothiazolo[5,4-D]pyrimidin-2-YL)isopropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

5-amino-4,6-dichloropyridimine (5413-85-4) + isopropyl isothiocyanate (2253-73-8) → (7-chloro[1,3]thiazolo[5,4-d]pyrimidin-2-yl)(isopropyl)amine (871266-86-3)

Guidance literature:

With caesium carbonate; In acetonitrile; at 50 ℃; for 16h;

DOI:10.1021/jo0517702

upstream raw materials:

5-amino-4,6-dichloropyridimine

isopropyl isothiocyanate

Refernces