C₁₈H₂₇NO₃

Base Information

• Chemical Name: C₁₈H₂₇NO₃
• CAS No.: 1390639-88-9
• Molecular Formula: C₁₈H₂₇NO₃
• Molecular Weight: 305.417
• Mol file: 1390639-88-9.mol

Synonyms:C₁₈H₂₇NO₃

Chemical Property of C₁₈H₂₇NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₈H₂₇NO₃

There total 1 articles about C₁₈H₂₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

C15H21NO3 (1390639-87-8) + allylmagnesium bromide (2622-05-1) → C18H27NO3 (1390639-88-9) + C18H27NO3 (1390639-89-0)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 7h; Inert atmosphere;

DOI:10.1039/c2ob25727k

Reference yield: 86.0%

C18H27NO3 (1390639-88-9) → C18H25NO2 (1390639-90-3)

Guidance literature:

With pyridine; methanesulfonyl chloride; In tetrahydrofuran; at 0 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c2ob25727k

Reference yield:

C18H27NO3 (1390639-88-9) → C17H23NO3 (1390639-94-7)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; methanesulfonyl chloride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

2: alpha AD-mix / water; acetone / 35 h / 0 - 4 °C / Inert atmosphere

3: silica-supported sodium periodate / dichloromethane / Inert atmosphere

With pyridine; alpha AD-mix; methanesulfonyl chloride; In tetrahydrofuran; dichloromethane; water; acetone;

DOI:10.1039/c2ob25727k

upstream raw materials:

C₁₅H₂₁NO₃

allylmagnesium bromide

Downstream raw materials:

C₁₇H₂₃NO₃

C₁₇H₂₃NO₃

C₁₇H₂₅NO₃

C₁₄H₂₂N₂O₂