2,2'-dimethyl-4,4'-biphenyldicarboxylic acid

Base Information

• Chemical Name: 2,2'-dimethyl-4,4'-biphenyldicarboxylic acid
• CAS No.: 117490-52-5
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.285
• Mol file: 117490-52-5.mol

Synonyms:2,2′-dimethyl-[1,1′-biphenyl]-4,4′-dicarboxylic acid

Chemical Property of 2,2'-dimethyl-4,4'-biphenyldicarboxylic acid

Chemical Property:

• Boiling Point: 452.4±45.0 °C(Predicted)
• PKA: 3.92±0.10(Predicted)
• Density: 1.272±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98.5% ^*data from raw suppliers

2,2'-Dimethyl-[1,1'-biphenyl]-4,4'-dicarboxylicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2'-dimethyl-4,4'-biphenyldicarboxylic acid

There total 13 articles about 2,2'-dimethyl-4,4'-biphenyldicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

dimethyl 2,2′-dimethyl-[1,1′-biphenyl]-4,4′-dicarboxylate (31458-18-1) → 2,2′-dimethyl-[1,1′-biphenyl]-4,4′-dicarboxylic acid (117490-52-5)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; methanol; water monomer; at 80 ℃;

DOI:10.1021/jacs.1c01361

Reference yield:

4C16H12O4(2-)*6Zr(4+)*4O(2-)*6HO(1-)*2H2O*C8H4O4(2-) → terephthalic acid (100-21-0) + 2,2′-dimethyl-[1,1′-biphenyl]-4,4′-dicarboxylic acid (117490-52-5)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃;

DOI:10.1021/jacs.6b04501

Reference yield:

4C16H12O4(2-)*6Zr(4+)*4O(2-)*6HO(1-)*C4H2O4(2-)*2H2O → 2,2′-dimethyl-[1,1′-biphenyl]-4,4′-dicarboxylic acid (117490-52-5) + (2E)-but-2-enedioic acid (110-17-8,26099-09-2)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃;

DOI:10.1021/jacs.6b04501

upstream raw materials:

dimethyl 2,2′-dimethyl-[1,1′-biphenyl]-4,4′-dicarboxylate

methyl 4-iodo-3-methylbenzoate

4-methoxycarbonyl-2-methylbenzeneboronic acid pinacol ester

4-Bromo-3-methylbenzoic acid methyl ester

Refernces

• 1、 Castner, Ashleigh T.,Johnson, Ben A.,Cohen, Seth M.,Ott, Sascha. "Mimicking the Electron Transport Chain and Active Site of [FeFe] Hydrogenases in One Metal-Organic Framework: Factors That Influence Charge Transport". supporting information. p. 7991 - 7999. Retrieved 2021/06/27.
• 2、 Grosjean, Sylvain,Hassan, Zahid,W?ll, Christof,Br?se, Stefan. "Diverse Multi-Functionalized Oligoarenes and Heteroarenes for Porous Crystalline Materials". . p. 1446 - 1460. Retrieved 2018/10/24.