(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Base Information

Chemical Name:(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide
CAS No.:1601479-86-0
Molecular Formula:C₂₃H₂₂F₃NO
Molecular Weight:385.429
Hs Code.:

Synonyms:(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Suppliers and Price of (R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Chemical Property:

Purity/Quality:

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Technology Process of (R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

There total 5 articles about (R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 226256-56-0,694495-47-1
cinacalcet

: 124-38-9,18923-20-1
carbon dioxide

: 1601479-86-0
(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Guidance literature:: With cyclopentadienyl iron(II) dicarbonyl dimer; tributylphosphine; phenylsilane; In acetonitrile; at 30 ℃; for 36h; under 760.051 Torr; Schlenk technique; Sealed tube;
DOI:10.1002/adsc.201900906

Reference yield:

: 1601479-84-8
(R)-(E)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)allyl)formamide

: 1601479-86-0
(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; hydrogen; sodium acetate; In benzonitrile; for 12h;
DOI:10.1016/j.tet.2013.10.014

Reference yield:

: 3886-70-2
(R)-1-(1-Naphthyl)ethylamine

: 1601479-86-0
(R)-N-(1-(naphthalen-1-yl)ethyl)-N-(3-(3-(trifluoromethyl)phenyl)propyl)formamide

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

2: 1 h / 0 - 50 °C

3: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium acetate / benzonitrile / 1 h / 20 °C

4: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium acetate; hydrogen / benzonitrile / 12 h

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; hydrogen; sodium acetate; triethylamine; In tetrahydrofuran; benzonitrile;
DOI:10.1016/j.tet.2013.10.014