2-Methyl-3-nitrobenzohydrazide

Base Information

• Chemical Name: 2-Methyl-3-nitrobenzohydrazide
• CAS No.: 869942-83-6
• Molecular Formula: C₈H₉N₃O₃
• Molecular Weight: 195.178
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID20393087
• Wikidata: Q82191709
• Mol file: 869942-83-6.mol

Synonyms:2-methyl-3-nitrobenzohydrazide;869942-83-6;2-methyl-3-nitrobenzenecarbohydrazide;2-Methyl-3-nitrobenzhydrazide;DTXSID20393087;BBL017856;MFCD03422927;STK487796;AKOS000159242;CS-0313124;FT-0754735;EN300-719420;12Y-0829;J-509955;F8889-9214;BORONIC ACID, B-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]-

Chemical Property of 2-Methyl-3-nitrobenzohydrazide

Chemical Property:

• Refractive Index: 1.607
• PSA: 100.94000
• Density: 1.345g/cm³
• LogP: 2.12110
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 195.06439116
• Heavy Atom Count: 14
• Complexity: 239

Purity/Quality:

98%min ^*data from raw suppliers

2-Methyl-3-nitrobenzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC=C1[N+](=O)[O-])C(=O)NN

Technology Process of 2-Methyl-3-nitrobenzohydrazide

There total 2 articles about 2-Methyl-3-nitrobenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-3-nitro-benzoic acid methyl ester (59382-59-1) → C8H9N3O3 (869942-83-6)

Guidance literature:

2-methyl-3-nitro-benzoic acid methyl ester; In methanol; at 0 ℃; for 0.166667h;

With hydrazine hydrate; In methanol; for 8h; Reflux;

DOI:10.1055/s-0036-1588747

Reference yield:

2-methyl-3-nitrobenzic acid (1975-50-4) → C8H9N3O3 (869942-83-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 0.17 h / 0 °C

1.2: 6 h / Reflux

2.1: methanol / 0.17 h / 0 °C

2.2: 8 h / Reflux

In methanol;

DOI:10.1055/s-0036-1588747

upstream raw materials:

2-methyl-3-nitrobenzic acid

2-methyl-3-nitro-benzoic acid methyl ester

Refernces

• 1、 Zhang, Guofu,Yu, Yidong,Zhao, Yiyong,Xie, Xiaoqiang,Ding, Chengrong. "Iron(III)/TEMPO-Catalyzed Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles by Oxidative Cyclization under Mild Conditions". . p. 1373 - 1377. Retrieved 2017/06/27.