N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide

Base Information

• Chemical Name: N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide
• CAS No.: 475296-09-4
• Molecular Formula: C₁₃H₁₄INO₂S
• Molecular Weight: 375.23
• Mol file: 475296-09-4.mol

Synonyms:N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide

Chemical Property of N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide

There total 1 articles about N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-iodophthalic anhydride (28418-88-4) + 2-methyl-1-methylthio-2-propylamine (36567-04-1) → 3-(1,1-dimethyl-2-methylthioethylimino)-4-iodo-3H-isobenzofuran-1-one + N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide (475296-09-4)

Guidance literature:

3-iodophthalic anhydride; 2-methyl-1-methylthio-2-propylamine; With triethylamine; In dichloromethane; at 20 ℃;

With methanesulfonyl chloride; triethylamine; In dichloromethane; at -10 ℃;

DOI:10.1016/j.bmc.2014.09.052

Reference yield: 79.0%

N-(1,1-dimethyl-2-methylthioethyl)-6-iodophthalic acid isoimide (475296-09-4) + 2-chloro-4-(pentafluoro-λ6-sulfanyl)aniline (165114-85-2) → N1-(2-chloro-4-pentafluorosulfanylphenyl)-N2-(1,1-dimethyl-2-methylthioethyl)-3-iodophthalamide

Guidance literature:

With trifluoroacetic acid; In acetonitrile; at 20 ℃; for 2h;

upstream raw materials:

3-iodophthalic anhydride

2-methyl-1-methylthio-2-propylamine