5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

Base Information

Chemical Name:5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]
CAS No.:1243139-05-0
Molecular Formula:C₂₇H₂₇N₆O₄PS
Molecular Weight:562.589
Hs Code.:

5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

Synonyms:5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

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Chemical Property of 5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

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Technology Process of 5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

There total 1 articles about 5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 942589-62-0
5-methyl-2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]pyrazolo[1,5-a]pyrimidin-7-ylamine

: 1243141-51-6
5-thiazolecarboxylic methyl ester 2-iodo-4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]

: 1243139-05-0
5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

Guidance literature:: With sodium hydrogencarbonate; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In 1,4-dioxane; water; at 90 ℃; for 3h; Inert atmosphere;

Reference yield: 65.0%

: 1243139-05-0
5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

: 1243138-79-5
5-thiazolecarboxylic acid 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]

Guidance literature:: 5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]-2-[phenyl-5-methyl-pyrazolo[1,5-a]pyrimidin-7-ylamine]; With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 48h;

With hydrogenchloride; In water;