2-(3,3-Difluoro-pyrrolidin-1-YL)-ethylamine

Base Information

Chemical Name:2-(3,3-Difluoro-pyrrolidin-1-YL)-ethylamine
CAS No.:867008-81-9
Molecular Formula:C6H12 F2 N2
Molecular Weight:150.17
Hs Code.:
DSSTox Substance ID:DTXSID80695190
Wikidata:Q82624287
Mol file:867008-81-9.mol

Synonyms:867008-81-9;2-(3,3-DIFLUORO-PYRROLIDIN-1-YL)-ETHYLAMINE;1-Pyrrolidineethanamine,3,3-difluoro-;2-(3,3-DIFLUOROPYRROLIDIN-1-YL)ETHANAMINE;C6H12F2N2;1-Pyrrolidineethanamine, 3,3-difluoro-;2-(3,3-difluoropyrrolidin-1-yl)ethylamine;SCHEMBL2442188;DTXSID80695190;LBIOMKUSKYNSCF-UHFFFAOYSA-N;AB64768;2-(3,3-Difluoro-pyrrolidin-1-yl)ethylamine;A1-16045;2-(3,3-DIFLUOROPYRROLIDIN-1-YL)ETHAN-1-AMINE

Suppliers and Price of 2-(3,3-Difluoro-pyrrolidin-1-YL)-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2-(3,3-Difluoro-pyrrolidin-1-yl)-ethylamine 95
5g
$ 1833.00

American Custom Chemicals Corporation
2-(3,3-DIFLUORO-PYRROLIDIN-1-YL)-ETHYLAMINE 95.00%
1G
$ 2760.45

American Custom Chemicals Corporation
2-(3,3-DIFLUORO-PYRROLIDIN-1-YL)-ETHYLAMINE 95.00%
5MG
$ 500.86

A1 Biochem Labs
2-(3,3-Difluoro-pyrrolidin-1-yl)-ethylamine 95%
2.5 g
$ 1300.00

Total 3 raw suppliers

Chemical Property of 2-(3,3-Difluoro-pyrrolidin-1-YL)-ethylamine

Chemical Property:

Boiling Point:172.6±40.0 °C(Predicted)
PKA:9.62±0.10(Predicted)
PSA：29.26000
Density:1.14±0.1 g/cm3(Predicted)
LogP:0.92430
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:150.09685472
Heavy Atom Count:10
Complexity:116

Purity/Quality:

98%min ^*data from raw suppliers

2-(3,3-Difluoro-pyrrolidin-1-yl)-ethylamine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC1(F)F)CCN

Technology Process of 2-(3,3-Difluoro-pyrrolidin-1-YL)-ethylamine

There total 1 articles about 2-(3,3-Difluoro-pyrrolidin-1-YL)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 867008-81-9
2-(3,3-difluoro-pyrrolidin-1-yl)ethylamine

Guidance literature:: With ammonia; hydrogen; In methanol; at 20 ℃; for 16h; under 15001.5 Torr; Autoclave;

Reference yield:

: 867008-81-9
2-(3,3-difluoro-pyrrolidin-1-yl)ethylamine

: 2-{[1-(4-chlorobenzoyl)azetidin-3-yl]methyl}-4-methoxy-2H-indazol-5-carboxylic acid

: 1442119-95-0
2-{[1-(4-chlorobenzoyl)azetidin-3-yl]methyl}-N-[2-(3,3-difluoropyrrolidin-1-yl)ethyl]-4-methoxy-2H-indazole-5-carboxamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield:

: 867008-81-9
2-(3,3-difluoro-pyrrolidin-1-yl)ethylamine

: 1350765-28-4
4-(4-chloro-2-((4-chloro-3-(trifluoromethyl)phenyl)sulfonamido)phenoxy)benzoic acid

: 1350765-11-5
C₂₆H₂₂Cl₂F₅N₃O₄S

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2011.10.038