3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID

Base Information

Chemical Name:3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID
CAS No.:866108-77-2
Molecular Formula:C₁₄H₁₀F₂O₂
Molecular Weight:248.229
Hs Code.:2916399090
Mol file:866108-77-2.mol

Synonyms:(3',5'-Difluorobiphenyl-3-yl)acetic acid; [1,1'-Biphenyl]-3-acetic acid, 3',5'-difluoro-

Suppliers and Price of 3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid 97%
5g
$ 1038.00

American Custom Chemicals Corporation
3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID 95.00%
500MG
$ 909.56

Alichem
2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid
5g
$ 1087.84

AK Scientific
3-Biphenyl-3',5'-difluoro-aceticacid
5g
$ 1487.00

Acrotein
3',5'-Difluoro-biphenyl-3-aceticacid 97%
0.5g
$ 228.80

Total 12 raw suppliers

Chemical Property of 3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID

Chemical Property:

Vapor Pressure:1.82E-06mmHg at 25°C
Refractive Index:1.563
Boiling Point:380.4°C at 760 mmHg
Flash Point:183.9°C
PSA：37.30000
Density:1.302g/cm³
LogP:3.25890

Purity/Quality:

97% ^*data from raw suppliers

2-(3',5'-Difluoro-[1,1'-biphenyl]-3-yl)aceticacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID

There total 3 articles about 3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 150529-73-0
methyl 2-(3-bromophenyl)acetatee

: 866108-77-2
3-(3,5-difluorophenyl)phenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Pd(PPh₃)4; aq. K₂CO₃ / toluene / 10 h / Heating

2: aq. NaOH

With sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In toluene; 1: Suzuki coupling;
DOI:10.1021/jm058220g

Reference yield:

: 156545-07-2
3,5-difluorophenylboronic acid

: 866108-77-2
3-(3,5-difluorophenyl)phenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Pd(PPh₃)4; aq. K₂CO₃ / toluene / 10 h / Heating

2: aq. NaOH

With sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In toluene; 1: Suzuki coupling;
DOI:10.1021/jm058220g