1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Base Information

Chemical Name:1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone
CAS No.:1428969-72-5
Molecular Formula:C₂₄H₂₁FN₂O₄S
Molecular Weight:452.506
Hs Code.:

Synonyms:1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Suppliers and Price of 1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

There total 4 articles about 1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 1428973-06-1
2-chloro-1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-phenylethanone

: 536-90-3,918666-97-4
m-Anisidine

: 1428969-72-5
1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Guidance literature:: In acetonitrile; at 100 ℃; for 0.75h; Microwave irradiation;

Reference yield:

: 399-52-0
5-fluoro-1H-indole

: 1428969-72-5
1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / toluene / 2 h / 55 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C

2.2: 3 h / 20 °C

3.1: acetonitrile / 0.75 h / 100 °C / Microwave irradiation

With pyridine; sodium hydride; In N,N-dimethyl-formamide; toluene; acetonitrile; mineral oil;

Reference yield:

: 1428972-76-2
2-chloro-1-(5-fluoro-1H-indol-3-yl)-2-phenylethanone

: 1428969-72-5
1-(5-fluoro-1-(methylsulfonyl)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C

1.2: 3 h / 20 °C

2.1: acetonitrile / 0.75 h / 100 °C / Microwave irradiation

With sodium hydride; In N,N-dimethyl-formamide; acetonitrile; mineral oil;