7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

Base Information

Chemical Name:7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine
CAS No.:1574388-95-6
Molecular Formula:C₂₄H₂₆N₆O₃S
Molecular Weight:478.575
Hs Code.:

Synonyms:7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

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Chemical Property of 7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

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Technology Process of 7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

There total 1 articles about 7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.2%

: 762262-09-9
(2-methoxypyridin-4-yl)boronic acid

: 1574389-45-9
7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-iodo-pyrrolo[2,3-d]pyrimidine

: 1574388-95-6
7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In acetonitrile; at 90 ℃; for 4h; Inert atmosphere;

Reference yield: 29.5%

: 1574388-95-6
7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

: 1574389-46-0
(4-nitrophenyl) N-[(1S)-1-[3-(difluoromethoxy)phenyl]ethyl]carbamate

: 1574388-96-7
4-[7-(benzenesulfonyl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidin-4-yl]-N-[(1S)-1-[3-(difluoromethoxy)phenyl]ethyl]-2,2-dimethyl-piperazine-1-carboxamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 50 ℃; for 1h;

Reference yield:

: 1574388-95-6
7-(benzenesulfonyl)-4-(3,3-dimethylpiperazin-1-yl)-6-(2-methoxy-4-pyridyl)pyrrolo[2,3-d]pyrimidine

: 1574381-52-4
N-[(1S)-1-[3-(difluoromethoxy)phenyl]ethyl]-4-[6-(2-methoxy-4-pyridyl)-7H-pyrrolo[2,3d]pyrimidin-4-yl]-2,2-dimethyl-piperazine-1-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 1 h / 50 °C

2: potassium hydroxide / methanol; water; tetrahydrofuran / 0.25 h / 50 °C

With triethylamine; potassium hydroxide; In tetrahydrofuran; methanol; water;