methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Base Information

Chemical Name:methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate
CAS No.:1620695-12-6
Molecular Formula:C₃₄H₄₈O₇
Molecular Weight:568.751
Hs Code.:

Synonyms:methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Suppliers and Price of methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

There total 21 articles about methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620695-31-9
C₃₁H₄₄O₆

: 88738-78-7
bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate

: 1620695-12-6
methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

: methyl (2E,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Guidance literature:: bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate; With 18-crown-6 ether; potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 - 0 ℃; for 0.5h;

C₃₁H₄₄O₆; In tetrahydrofuran; toluene; at -78 - 0 ℃; for 8h;
DOI:10.1002/hlca.201300326

Reference yield:

: 4,5-anhydro-3-deoxy-1,2-O-(1-methylethylidene)-D-xylohexitol

: 1620695-12-6
methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

: methyl (2E,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Guidance literature:: Multi-step reaction with 8 steps

1.1: sodium hydrogencarbonate; tetrachloromethane; triphenylphosphine / 4 h / Reflux

2.1: sodium / diethyl ether / 8 h / 20 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran; paraffin oil / 0.25 h / 0 °C

3.2: 6 h / 0 - 20 °C

4.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 48 h / Inert atmosphere; Reflux

5.1: platinum(IV) oxide; hydrogen / ethyl acetate / 8 h / 20 °C

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere

7.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C

7.2: -30 °C

8.1: 18-crown-6 ether; potassium hexamethylsilazane / tetrahydrofuran; toluene / 0.5 h / -78 - 0 °C

8.2: 8 h / -78 - 0 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; tetrachloromethane; platinum(IV) oxide; oxalyl dichloride; 18-crown-6 ether; tetrabutyl ammonium fluoride; hydrogen; sodium; potassium hexamethylsilazane; sodium hydride; sodium hydrogencarbonate; dimethyl sulfoxide; triphenylphosphine; In tetrahydrofuran; diethyl ether; dichloromethane; ethyl acetate; toluene; paraffin oil; 7.1: |Swern Oxidation / 7.2: |Swern Oxidation / 8.1: |Wittig Olefination / 8.2: |Wittig Olefination;
DOI:10.1002/hlca.201300326

Reference yield:

: 117064-90-1
(2R)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]but-3-en-2-ol

: 1620695-12-6
methyl (2Z,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

: methyl (2E,4S,5S,6S,9S)-9-(benzyloxy)-10-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-ethyl-5-[(4-methoxybenzyl)oxy]-6-methyldec-2-enoate

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / tetrahydrofuran; paraffin oil / 0.25 h / 0 °C

1.2: 6 h / 0 - 20 °C

2.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 48 h / Inert atmosphere; Reflux

3.1: platinum(IV) oxide; hydrogen / ethyl acetate / 8 h / 20 °C

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere

5.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C

5.2: -30 °C

6.1: 18-crown-6 ether; potassium hexamethylsilazane / tetrahydrofuran; toluene / 0.5 h / -78 - 0 °C

6.2: 8 h / -78 - 0 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; platinum(IV) oxide; oxalyl dichloride; 18-crown-6 ether; tetrabutyl ammonium fluoride; hydrogen; potassium hexamethylsilazane; sodium hydride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane; ethyl acetate; toluene; paraffin oil; 5.1: |Swern Oxidation / 5.2: |Swern Oxidation / 6.1: |Wittig Olefination / 6.2: |Wittig Olefination;
DOI:10.1002/hlca.201300326