(2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol

Base Information

• Chemical Name: (2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol
• CAS No.: 65052-93-9
• Molecular Formula: C₂₁H₁₈O₈
• Molecular Weight: 398.369
• Mol file: 65052-93-9.mol

Synonyms:(2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol

Chemical Property of (2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol

There total 4 articles about (2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.6%

C49H42O8 (1242246-45-2) → (2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol (65052-93-9)

Guidance literature:

With 30% Pd/C; hydrogen; In ethanol; at 20 ℃; for 4h; under 1500.15 Torr;

DOI:10.1016/j.bmc.2010.06.077

Reference yield:

(2R,3S,4S)-2,3-trans-3,4-trans-4-(2,4,6-trihydroxyphenyl)flavan-3,3',4',7-tetraol (69082-77-5) → (2R,3S,4R)-2,3-trans-3,4-cis-4-(2,4,6-trihydroxyphenyl)flavan-3,3',4',7-tetraol (78174-80-8) + (2S,3S,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol (65052-93-9,94942-00-4,125136-15-4,125136-16-5,125136-17-6,125136-18-7)

Guidance literature:

benzophenone; In acetone; Irradiation;

DOI:10.1039/P19810001220

Reference yield:

(2S,3R,4S)-4α-(2,4,6-trihydroxyphenyl)flavan-3,3',4',7-tetraol (125090-60-0) → 2-[(2R,3R,4S)-2-(3,4-Dihydroxy-phenyl)-3,7-dihydroxy-chroman-4-yl]-benzene-1,3,5-triol (125090-62-2) + (2S,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol (125136-18-7) + (2R,3R,4S)-4-(2,4-Dihydroxy-phenyl)-2-(3,4-dihydroxy-phenyl)-chroman-3,5,7-triol (65052-93-9) + (2S,3S,4R)-4-(3,4-Dihydroxy-phenyl)-2-(2,4-dihydroxy-phenyl)-chroman-3,5,7-triol (125090-65-5)

Guidance literature:

With sodium hydrogencarbonate; sodium carbonate; at 50 ℃; for 4h; Further byproducts given. Title compound not separated from byproducts;

upstream raw materials:

(2R,3S,4S)-2,3-trans-3,4-trans-4-(2,4,6-trihydroxyphenyl)flavan-3,3',4',7-tetraol

(2S,3R,4S)-4α-(2,4,6-trihydroxyphenyl)flavan-3,3',4',7-tetraol

C₄₉H₄₂O₈

Downstream raw materials:

Acetic acid (2R,3R,4S)-4-(2,4-dimethoxy-phenyl)-2-(3,4-dimethoxy-phenyl)-5,7-dimethoxy-chroman-3-yl ester

2,3-cis-3,4-cis-3',4',5,7-tetramethoxy-4-(2,4-dimethoxyphenyl)flavan-3-ol

cyanidin chloride

fisetinidin chloride