N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine

Base Information

• Chemical Name: N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine
• CAS No.: 308822-37-9
• Molecular Formula: C₁₆H₂₃BrN₄
• Molecular Weight: 351.289
• Mol file: 308822-37-9.mol

Synonyms:N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine

Chemical Property of N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine

There total 1 articles about N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-azido-3-iodopropane (58503-62-1) + [2-Bromo-1-p-tolyl-prop-(E)-ylidene]-isopropyl-amine → N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine (308822-37-9)

Guidance literature:

[2-Bromo-1-p-tolyl-prop-(E)-ylidene]-isopropyl-amine; With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

1-azido-3-iodopropane; at -78 - 0 ℃; for 5h; Further stages.;

DOI:10.1021/jo000724t

Reference yield: 89.0%

N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine (308822-37-9) → 6-azido-3-bromo-3-methyl-1-(4-methylphenyl)-2-hexanone (326893-32-7)

Guidance literature:

With hydrogenchloride; In methanol; for 2h; Heating;

DOI:10.1021/jo000724t

Reference yield: 44.0%

N-[5-azido-2-bromo-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine (308822-37-9) → N-[5-azido-2-methyl-2-(4-methylphenyl)-1-butylidene]isopropylamine

Guidance literature:

With tin(ll) chloride; In methanol; at 20 ℃; for 4h;

DOI:10.1021/jo000724t

upstream raw materials:

1-azido-3-iodopropane

Downstream raw materials:

6-azido-3-bromo-3-methyl-1-(4-methylphenyl)-2-hexanone

3-methyl-2-(4-methylphenyl)pyridine

5-bromo-5-methyl-6-(4-methylphenyl)-2,3,4,5-tetrahydropyridine