1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene

Base Information

• Chemical Name: 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene
• CAS No.: 1203642-90-3
• Molecular Formula: C₂₀H₃₃NO₁₀
• Molecular Weight: 447.483
• Mol file: 1203642-90-3.mol

Synonyms:1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene

Chemical Property of 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene

There total 5 articles about 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-chloro-3,6,9-trioxadecane (52995-76-3) + 1,2-dihydroxy-4-nitrobenzene (3316-09-4) → 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene (1203642-90-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 19h; Inert atmosphere;

Reference yield: 54.0%

1,2-bis[2-[2-(2-methoxyethoxy)-ethoxy]ethoxy]-benzene (57721-95-6) → 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene (1203642-90-3)

Guidance literature:

With nitric acid; silica gel; In dichloromethane; for 0.0833333h;

Reference yield:

triethylene glucol monomethyl ether (112-35-6,95507-80-5) → 1,2-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-nitrobenzene (1203642-90-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridine; thionyl chloride / toluene / Heating

1.2: 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 19 h / 140 °C / Inert atmosphere

With pyridine; thionyl chloride; potassium carbonate; In N,N-dimethyl-formamide; toluene;

upstream raw materials:

triethylene glucol monomethyl ether

1-chloro-3,6,9-trioxadecane

1,2-dihydroxy-4-nitrobenzene

benzene-1,2-diol

Downstream raw materials:

3,4-di-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}aniline