N'-Nitrosonornicotine-N-b-D-glucuronide

Base Information

• Chemical Name: N'-Nitrosonornicotine-N-b-D-glucuronide
• CAS No.: 864071-82-9
• Molecular Formula: C₁₅H₁₉N₃O₇
• Molecular Weight: 353.332
• Hs Code.: 29389090
• Mol file: 864071-82-9.mol

Synonyms:N'-NitrosonornicotineN-glucuronide

Chemical Property of N'-Nitrosonornicotine-N-b-D-glucuronide

Chemical Property:

• PSA: 146.60000
• LogP: -2.53970

Purity/Quality:

≥95% ^*data from raw suppliers

N''-Nitrosonornicotine-N-b-D-glucuronide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N''-Nitrosonornicotine-N-b-D-glucuronide (cas# 864071-82-9) is a compound useful in organic synthesis.

Technology Process of N'-Nitrosonornicotine-N-b-D-glucuronide

There total 2 articles about N'-Nitrosonornicotine-N-b-D-glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(1-Nitroso-pyrrolidin-2-yl)-1-((2R,3R,4S,5S,6S)-3,4,5-triacetoxy-6-methoxycarbonyl-tetrahydro-pyran-2-yl)-pyridinium; bromide → pyridyl-N-β-D-glucopyranuronosyl-N'-nitrosonornicotinium inner salt (864071-82-9)

Guidance literature:

With sodium hydroxide; at 20 ℃; for 16h;

DOI:10.1021/tx000262e

Reference yield:

3-(1-nitroso-pyrrolidin-2-yl)-pyridine (80508-23-2,350508-22-4,350508-30-4,61601-78-3,84237-38-7) → pyridyl-N-β-D-glucopyranuronosyl-N'-nitrosonornicotinium inner salt (864071-82-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 h / 55 - 60 °C / N₂

2: aq. NaOH / 16 h / 20 °C

With sodium hydroxide;

DOI:10.1021/tx000262e

upstream raw materials:

3-(1-nitroso-pyrrolidin-2-yl)-pyridine