4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ⁴]oxazaborino[3,4-a]azepine

Base Information

• Chemical Name: 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ⁴]oxazaborino[3,4-a]azepine
• CAS No.: 1357027-07-6
• Molecular Formula: C₂₇H₂₇BBrN₃O
• Molecular Weight: 500.246
• Mol file: 1357027-07-6.mol

Synonyms:4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ⁴]oxazaborino[3,4-a]azepine

Chemical Property of 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ⁴]oxazaborino[3,4-a]azepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ⁴]oxazaborino[3,4-a]azepine

There total 3 articles about 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ⁴]oxazaborino[3,4-a]azepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

BrC6H4N2(1+)*B(C6H5)4(1-)=[BrC6H4N2][B(C6H5)4] (4696-64-4) + (α-hexahydroazepinylidene)-propanone (130721-65-2) → 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ4]oxazaborino[3,4-a]azepine (1357027-07-6)

Guidance literature:

In dichloromethane; toluene; at 5 ℃; for 3h; Reflux;

DOI:10.1016/j.jorganchem.2011.11.004

Reference yield:

O-methylcaprolactim (2525-16-8) → 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ4]oxazaborino[3,4-a]azepine (1357027-07-6)

Guidance literature:

Multi-step reaction with 3 steps

1: bis(acetylacetonate)nickel(II) / 24 h / 100 °C

2: methanol; sodium / 1 h / Reflux

3: dichloromethane; toluene / 3 h / 5 °C / Reflux

With methanol; bis(acetylacetonate)nickel(II); sodium; In dichloromethane; toluene;

DOI:10.1016/j.jorganchem.2011.11.004

Reference yield:

3-(hexahydro-2-azepinylidene)pentan-2,4-dione (108140-18-7) → 4-(4-bromophenyldiazenyl)-3-methyl-1,1-diphenyl-6,7,8,9-tetrahydro-5H-[1,3,2 λ4]oxazaborino[3,4-a]azepine (1357027-07-6)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; sodium / 1 h / Reflux

2: dichloromethane; toluene / 3 h / 5 °C / Reflux

With methanol; sodium; In dichloromethane; toluene;

DOI:10.1016/j.jorganchem.2011.11.004

upstream raw materials:

O-methylcaprolactim

BrC₆H₄N₂⁽¹⁺⁾*B(C₆H₅)4^(1-)=[BrC₆H₄N₂][B(C₆H₅)4]

(α-hexahydroazepinylidene)-propanone

3-(hexahydro-2-azepinylidene)pentan-2,4-dione

Downstream raw materials:

4-acetyl-2-(4-bromophenyl)-1,1-diphenyl-2,5,6,7,8,9-hexahydro-1H-[1,2,4,3 λ⁴]-triazaborino[4,5-d]azepine