(E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

Base Information

Chemical Name:(E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine
CAS No.:1399879-66-3
Molecular Formula:C₂₈H₃₁N₇O₂
Molecular Weight:497.6
Hs Code.:

Synonyms:(E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

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Technology Process of (E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

There total 4 articles about (E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 299907-60-1
4,4'-(6-hydrazinylpyrimidine-2,4-diyl)dimorpholine

: 10511-51-0
1-Benzylindole-3-carboxaldehyde

: 1399879-66-3
(E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

Guidance literature:: With acetic acid; In ethanol; Reflux;
DOI:10.1002/ardp.201200074

Reference yield:

: 100-44-7
benzyl chloride

: 1399879-66-3
(E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 °C

2: acetic acid / ethanol / Reflux

With potassium carbonate; acetic acid; In ethanol; N,N-dimethyl-formamide;
DOI:10.1002/ardp.201200074

Reference yield:

: 10244-24-3
2,4-[bis(morpholino)]-6-chloropyrimidine

: 1399879-66-3
(E)-4,4'-(6-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / water / 80 °C

2: acetic acid / ethanol / Reflux

With hydrazine hydrate; acetic acid; In ethanol; water;
DOI:10.1002/ardp.201200074