1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene

Base Information

• Chemical Name: 1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene
• CAS No.: 1385138-15-7
• Molecular Formula: C₅₆H₈₂N₄O₂
• Molecular Weight: 843.293
• Mol file: 1385138-15-7.mol

Synonyms:1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene

Chemical Property of 1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene

There total 2 articles about 1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(2Z,2'Z)-1,1'-(1,4-phenylene)bis(3-(4-(hexadecyloxy)phenyl)-3-hydroxyprop-2-en-1-one) → 1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene (1385138-15-7)

Guidance literature:

With acetic acid; hydrazine; In tetrahydrofuran; for 24h; Reflux;

DOI:10.1016/j.tet.2012.05.060

Reference yield:

1,4-benzenedicarboxylic acid dimethyl ester (120-61-6) + 4-(hexadecyloxy)acetophenone (17788-58-8) → 1,4-bis(5-(4-(hexadecyloxy)phenyl)-1H-pyrazol-3-yl)benzene (1385138-15-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / Reflux; Inert atmosphere

1.2: 24 h / Reflux

2.1: acetic acid; hydrazine / tetrahydrofuran / 24 h / Reflux

With sodium hydride; acetic acid; hydrazine; In tetrahydrofuran;

DOI:10.1016/j.tet.2012.05.060

upstream raw materials:

1,4-benzenedicarboxylic acid dimethyl ester

4-(hexadecyloxy)acetophenone