Technology Process of 1,3-bis(2-methylphenyl)-4,5,6,7-tetrahydro-3H-[1,3]diazepin-1-ium tetrafluoroborate
There total 1 articles about 1,3-bis(2-methylphenyl)-4,5,6,7-tetrahydro-3H-[1,3]diazepin-1-ium tetrafluoroborate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1,4-Diiodobutane; N,N'-bis(2-methylphenyl)formamidine;
With
potassium carbonate;
In
acetonitrile;
Reflux;
Inert atmosphere;
With
sodium tetrafluoroborate;
In
water; acetonitrile;
at 20 ℃;
for 0.166667h;
DOI:10.1002/ejic.200801179
- Guidance literature:
-
With
potassium hexamethylsilazane;
In
tetrahydrofuran; diethyl ether;
(Ar), KN(SiMe3)2 and carbene precursor (1:1) dissolved in Et2O, stirred for 30 min, filtered into soln. of 0.5 equiv. of Rh complex in THF, stirred at room temp. for 1 h; evapd.(vac.), washed (hexane), dried (vac.), dissolved (CH2Cl2), pptd.(Et2O);
DOI:10.1002/ejic.200801179
- Guidance literature:
-
1,3-bis(2-methylphenyl)-4,5,6,7-tetrahydro-3H-[1,3]diazepin-1-ium tetrafluoroborate;
With
potassium tert-butylate;
In
toluene;
at 20 ℃;
for 18h;
Inert atmosphere;
Schlenk technique;
1,3-divinyl-1,1,3,3-tetramethyldisiloxane palladium(0);
With
tetramethyldivinyldisiloxane;
In
toluene;
at 20 ℃;
for 17h;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/om300930w
