tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate

Base Information

Chemical Name:tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate
CAS No.:1254705-13-9
Molecular Formula:C₂₈H₄₀N₂O₃
Molecular Weight:452.637
Hs Code.:

Synonyms:tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate

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Chemical Property of tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate

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Technology Process of tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate

There total 1 articles about tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1254705-05-9
tert-butyl 4-(4-hydroxyphenyl)-4-phenylbutyl(methyl)carbamate

: 7250-67-1
1-(2-chloroethyl)pyrrolidine hydrochloride

: 1254705-13-9
tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate

Guidance literature:: tert-butyl 4-(4-hydroxyphenyl)-4-phenylbutyl(methyl)carbamate; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.166667h;

1-(2-chloroethyl)pyrrolidine hydrochloride; In N,N-dimethyl-formamide; mineral oil; at 70 ℃; for 1h;
DOI:10.1021/jm100666w

Reference yield: 87.0%

: 1254705-13-9
tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate

: 1254704-90-9
N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butan-1-amine

Guidance literature:: tert-butyl methyl(4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butyl)carbamate; With trifluoroacetic acid; at 60 ℃; for 0.0333333h;

With sodium hydroxide; In dichloromethane; water;
DOI:10.1021/jm100666w