3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide

Base Information

Chemical Name:3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide
CAS No.:1227936-78-8
Molecular Formula:C₂₂H₁₆Cl₂N₄O₄
Molecular Weight:471.299
Hs Code.:

Synonyms:3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide

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Chemical Property of 3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide

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Technology Process of 3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide

There total 1 articles about 3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 886371-76-2
6-chloro-5-methoxy-pyridin-2-amine

: 1170079-53-4
methyl 2-amino-4-({[(4-chlorophenyl)methyl]amino}carbonyl)benzoate

: 1227936-78-8
3-[6-chloro-5-(methyloxy)-2-pyridinyl]-N-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydro-7-quinazolinecarboxamide

Guidance literature:: bis(trichloromethyl) carbonate; methyl 2-amino-4-({[(4-chlorophenyl)methyl]amino}carbonyl)benzoate; With dmap; In dichloromethane; at -78 ℃; Inert atmosphere;

6-chloro-5-methoxy-pyridin-2-amine; With sodium hydride; In dichloromethane; N,N-dimethyl-formamide; for 2h; Inert atmosphere;