Technology Process of 2-(3-bromo-2-nitrophenyl)acetic acid
There total 4 articles about 2-(3-bromo-2-nitrophenyl)acetic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
water; acetone;
Solvent;
Reflux;
- Guidance literature:
-
C8H8BrNO2;
With
sodium hydrogencarbonate; sodium hydroxide;
at 0 ℃;
for 0.166667h;
Inert atmosphere;
Darkness;
With
Oxone; ethylenediaminetetraacetic acid;
In
water; acetone;
for 4h;
Cooling with ice;
Inert atmosphere;
Darkness;
DOI:10.1039/c5ra04984a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrazine hydrate / diethylene glycol / 1 h / 80 °C / Inert atmosphere
1.2: 2 h / 120 °C / Inert atmosphere
1.3: Inert atmosphere
2.1: sodium hydroxide; sodium hydrogencarbonate / 0.17 h / 0 °C / Inert atmosphere; Darkness
2.2: 4 h / Cooling with ice; Inert atmosphere; Darkness
With
sodium hydrogencarbonate; hydrazine hydrate; sodium hydroxide;
In
diethylene glycol;
1.1: |Wolff-Kishner Reduction;
DOI:10.1039/c5ra04984a
