C₂₂H₂₃ClN₂O₂

Base Information

• Chemical Name: C₂₂H₂₃ClN₂O₂
• CAS No.: 1243531-74-9
• Molecular Formula: C₂₂H₂₃ClN₂O₂
• Molecular Weight: 382.89
• Mol file: 1243531-74-9.mol

Synonyms:C₂₂H₂₃ClN₂O₂

Chemical Property of C₂₂H₂₃ClN₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₂₂H₂₃ClN₂O₂

There total 1 articles about C₂₂H₂₃ClN₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-benzyl-1-oxa-6-azaspiro[2,5]-octane (19867-34-6) + 3-hydroxy-2-chloroquinoline (128676-94-8) → C22H23ClN2O2 (1243531-74-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; regioselective reaction;

DOI:10.1016/j.tetlet.2010.06.061

Reference yield: 83.0%

C22H23ClN2O2 (1243531-74-9) → C22H22N2O2 (1243531-90-9)

Guidance literature:

With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 125 ℃; regioselective reaction; Inert atmosphere; sealed tube;

DOI:10.1016/j.tetlet.2010.06.061

upstream raw materials:

N-benzyl-1-oxa-6-azaspiro[2,5]-octane

3-hydroxy-2-chloroquinoline

Downstream raw materials:

C₂₂H₂₂N₂O₂

Refernces