N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester

Base Information

• Chemical Name: N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester
• CAS No.: 1011269-13-8
• Molecular Formula: C₁₉H₁₉NO₂
• Molecular Weight: 293.365
• Mol file: 1011269-13-8.mol

Synonyms:N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester

Chemical Property of N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester

There total 6 articles about N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

tert-butyl phenylcarbamate (3422-01-3) + 1-Bromo-2-phenylacetylene (932-87-6) → N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester (1011269-13-8)

Guidance literature:

With potassium phosphate; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; In toluene; at 80 ℃; for 40h;

DOI:10.1021/ol703077g

Reference yield: 55.0%

tert-butyl phenylcarbamate (3422-01-3) + (2,2-dichlorovinyl)benzene (698-88-4) → N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester (1011269-13-8)

Guidance literature:

With potassium tert-butylate; In acetone; at 80 ℃; for 23h; Schlenk technique;

Reference yield: 42.0%

tert-butyl phenylcarbamate (3422-01-3) + phenylacetylene (536-74-3) → N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester (1011269-13-8)

Guidance literature:

tert-butyl phenylcarbamate; With pyridine; oxygen; sodium carbonate; copper dichloride; In toluene; at 70 ℃; for 0.25h;

phenylacetylene; In toluene; at 70 ℃; for 8h;

DOI:10.1021/acs.joc.0c01258

upstream raw materials:

tert-butyl phenylcarbamate

1-Bromo-2-phenylacetylene

(2,2-dichlorovinyl)benzene

phenylacetylene

Downstream raw materials:

3-phenyl-5-phenyloxazol-2(3H)-one

(3-hydroxy-2-phenyl-3H-inden-1-yl)phenylcarbamic acid tert-butyl ester

(1-hydroxy-3-phenyl-1H-inden-2-yl)phenylcarbamic acid tert-butyl ester

[3-(tert-butoxycarbonylphenylamino)-2-phenyl-1H-inden-1-yl]acetic acid methyl ester