Technology Process of 4-amino-5-{[4-(ethylthio)phenoxy]methyl}-4H-1,2,4-triazole-3-thiol
There total 3 articles about 4-amino-5-{[4-(ethylthio)phenoxy]methyl}-4H-1,2,4-triazole-3-thiol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
carbon disulfide; 2-[4-(ethylthio)phenoxy]acetohydrazide;
With
potassium hydroxide;
In
methanol;
at 20 ℃;
With
hydrazine hydrate;
In
water;
Further stages.;
Heating;
DOI:10.1016/j.ejmech.2006.10.010
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 92 percent / hydrazine hydrate / methanol / Heating
2.1: potassium hydroxide / methanol / 20 °C
2.2: 80 percent / hydrazine hydrate / H2O / Heating
With
potassium hydroxide; hydrazine hydrate;
In
methanol;
DOI:10.1016/j.ejmech.2006.10.010
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / acetone / 3 h / Heating
2.1: 92 percent / hydrazine hydrate / methanol / Heating
3.1: potassium hydroxide / methanol / 20 °C
3.2: 80 percent / hydrazine hydrate / H2O / Heating
With
potassium hydroxide; potassium carbonate; hydrazine hydrate;
In
methanol; acetone;
DOI:10.1016/j.ejmech.2006.10.010
