C₁₆H₂₉NO₆

Base Information

• Chemical Name: C₁₆H₂₉NO₆
• CAS No.: 263272-45-3
• Molecular Formula: C₁₆H₂₉NO₆
• Molecular Weight: 331.409

Synonyms:C₁₆H₂₉NO₆

Chemical Property of C₁₆H₂₉NO₆

Chemical Property:

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Technology Process of C₁₆H₂₉NO₆

There total 1 articles about C₁₆H₂₉NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-(tert-butoxycarbonylamino)hexanoic acid (6404-29-1) + isobutyl chloroformate (543-27-1) → C16H29NO6 (263272-45-3)

Guidance literature:

With 4-methyl-morpholine; In dichloromethane; at -10 ℃; for 0.0833333h;

DOI:10.1016/0223-5234(92)90025-V

Reference yield: 87.9%

C16H29NO6 (263272-45-3) + H-Tyr(O-Pic)-octylamide → Boc-EACA-Tyr(O-Pic)-NH-(CH2)7-CH3 (325464-22-0)

Guidance literature:

With triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1248/cpb.48.1964

Reference yield: 73.1%

C16H29NO6 (263272-45-3) + H-Tyr(O-Pic)-Tra-octyl ester → Boc-EACA-Tyr(O-Pic)-Tra-octyl ester (325464-20-8)

Guidance literature:

With methoxybenzene; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1248/cpb.48.1964

upstream raw materials:

6-(tert-butoxycarbonylamino)hexanoic acid

isobutyl chloroformate

Downstream raw materials:

Fmoc-Lys(Acp-BOC)-OBzl

{4-[(S)-2-(6-tert-Butoxycarbonylamino-hexanoylamino)-3-phenyl-propionylamino]-phenyl}-acetic acid benzyl ester

carbonic acid 2-bromo-benzyl ester 4-[2-(6-tert-butoxycarbonylamino-hexanoylamino)-2-(1,1-dimethyl-propylcarbamoyl)-ethyl]-phenyl ester

carbonic acid 2-bromo-benzyl ester 4-[2-(6-tert-butoxycarbonylamino-hexanoylamino)-2-(3-methyl-butylcarbamoyl)-ethyl]-phenyl ester

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