C₁₆H₁₅N₃O₃

Base Information

Chemical Name:C₁₆H₁₅N₃O₃
CAS No.:1236303-34-6
Molecular Formula:C₁₆H₁₅N₃O₃
Molecular Weight:297.313
Hs Code.:

C<sub>16</sub>H<sub>15</sub>N<sub>3</sub>O<sub>3</sub>

Synonyms:C₁₆H₁₅N₃O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₁₅N₃O₃

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Technology Process of C₁₆H₁₅N₃O₃

There total 7 articles about C₁₆H₁₅N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1236303-37-9
8-ethyl-4-methoxy-N-phenyl-5H-pyrano[4,3-d]pyrimidine-2-carboxamide

: 1236303-34-6
C₁₆H₁₅N₃O₃

Guidance literature:: With chloro-trimethyl-silane; water; sodium iodide; In acetonitrile; at 65 ℃; Darkness; Inert atmosphere;
DOI:10.1002/asia.201000073

Reference yield: 71.0%

: 1236303-33-5
C₁₀H₁₀N₂O₄

: 62-53-3
aniline

: 1236303-34-6
C₁₆H₁₅N₃O₃

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1002/asia.201000073

Reference yield:

: 848891-83-8
2-chloro-8-ethyl-4-methoxy-5H-pyrano[4,3-d]pyrimidine

: 1236303-34-6
C₁₆H₁₅N₃O₃

Guidance literature:: Multi-step reaction with 5 steps

1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; triethylamine / 5 h / 90 °C / 6965.99 Torr / Inert atmosphere

2: lithium hydroxide monohydrate; water / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 °C / Inert atmosphere

4: sodium hydrogencarbonate / dichloromethane / 2 h / Inert atmosphere

5: chloro-trimethyl-silane; water; sodium iodide / acetonitrile / 65 °C / Darkness; Inert atmosphere

With chloro-trimethyl-silane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; oxalyl dichloride; lithium hydroxide monohydrate; water; sodium hydrogencarbonate; triethylamine; N,N-dimethyl-formamide; sodium iodide; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1002/asia.201000073