3-Benzyl-5,7-dimethyl-3H-8λ⁵-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide

Base Information

• Chemical Name: 3-Benzyl-5,7-dimethyl-3H-8λ⁵-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide
• CAS No.: 241822-57-1
• Molecular Formula: C₁₄H₁₅N₅
• Molecular Weight: 253.307
• Mol file: 241822-57-1.mol

Synonyms:3-Benzyl-5,7-dimethyl-3H-8λ⁵-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide

Chemical Property of 3-Benzyl-5,7-dimethyl-3H-8λ⁵-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Benzyl-5,7-dimethyl-3H-8λ⁵-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide

There total 3 articles about 3-Benzyl-5,7-dimethyl-3H-8λ⁵-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-Amino-3-benzyl-5,7-dimethyl-3H-8λ5-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium chloride → 3-Benzyl-5,7-dimethyl-3H-8λ5-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide (241822-57-1)

Guidance literature:

With sodium hydroxide; water; at 0 ℃;

DOI:10.1039/a900942f

Reference yield:

Benzyl dicyanamide (35695-46-6) → 3-Benzyl-5,7-dimethyl-3H-8λ5-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide (241822-57-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 64 percent / hydrazine monohydrate / various solvent(s) / Ambient temperature

2: 88 percent / HCl, H₂O / various solvent(s) / 1 h / Heating

3: 78 percent / NaOH, H₂O / 0 °C

With hydrogenchloride; sodium hydroxide; water; hydrazine hydrate; In various solvent(s);

DOI:10.1039/a900942f

Reference yield:

3,5-Diamino-4-benzyl-1,2,4-triazole (241822-66-2) → 3-Benzyl-5,7-dimethyl-3H-8λ5-<1,2,4>triazolo<1,5-a>pyrimidin-8-ylium-2-aminide (241822-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / HCl, H₂O / various solvent(s) / 1 h / Heating

2: 78 percent / NaOH, H₂O / 0 °C

With hydrogenchloride; sodium hydroxide; water; In various solvent(s);

DOI:10.1039/a900942f

upstream raw materials:

Benzyl dicyanamide

3,5-Diamino-4-benzyl-1,2,4-triazole