Technology Process of C38H48FN5O9S
There total 5 articles about C38H48FN5O9S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; HATU;
In
N,N-dimethyl-formamide;
at 20 ℃;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 20 °C
2.1: hydrogen / rhodium on alumina / ethyl acetate / 16 h / 760.05 Torr
3.1: sodium hydroxide; ethanol; water / toluene / 5 - 6 h / 5 - 10 °C
3.2: 1 h / 5 - 10 °C / pH 3 - 4
4.1: dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
With
dmap; sodium hydroxide; ethanol; water; hydrogen; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; HATU;
rhodium on alumina;
In
ethyl acetate; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogen / rhodium on alumina / ethyl acetate / 16 h / 760.05 Torr
2.1: sodium hydroxide; ethanol; water / toluene / 5 - 6 h / 5 - 10 °C
2.2: 1 h / 5 - 10 °C / pH 3 - 4
3.1: dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
With
dmap; sodium hydroxide; ethanol; water; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; HATU;
rhodium on alumina;
In
ethyl acetate; N,N-dimethyl-formamide; toluene;