(2-(4-Methoxyphenyl)thiazol-4-yl)methanamine

Base Information

• Chemical Name: (2-(4-Methoxyphenyl)thiazol-4-yl)methanamine
• CAS No.: 857997-91-2
• Molecular Formula: C₁₁H₁₂N₂OS
• Molecular Weight: 220.295
• Hs Code.: 2934100090
• ChEMBL ID: CHEMBL4539580
• DSSTox Substance ID: DTXSID30586185
• Wikidata: Q82478261
• Mol file: 857997-91-2.mol

Synonyms:857997-91-2;(2-(4-Methoxyphenyl)thiazol-4-yl)methanamine;C-[2-(4-METHOXY-PHENYL)-THIAZOL-4-YL]-METHYLAMINE;[2-(4-METHOXYPHENYL)-1,3-THIAZOL-4-YL]METHANAMINE;1-[2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanamine;F2189-0355;CHEMBL4539580;DTXSID30586185;AKOS000320860;AB27129;MCULE-9353933693;DB-076445;CS-0456457;EN300-95693;2-(4-METHOXYPHENYL)-4-THIAZOLEMETHANAMINE;A863433;Z105197314

Chemical Property of (2-(4-Methoxyphenyl)thiazol-4-yl)methanamine

Chemical Property:

• PSA: 76.38000
• LogP: 2.97770
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 220.06703418
• Heavy Atom Count: 15
• Complexity: 195

Purity/Quality:

98%min ^*data from raw suppliers

C-[2-(4-Methoxy-phenyl)-thiazol-4-yl]-methylamine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=NC(=CS2)CN

Technology Process of (2-(4-Methoxyphenyl)thiazol-4-yl)methanamine

There total 1 articles about (2-(4-Methoxyphenyl)thiazol-4-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxyphenylacetamide (3424-93-9) → C-[2-(4-methoxy-phenyl)-thiazol-4-yl]-methylamine (857997-91-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetraphosphorus decasulfide

2.1: ethanol; tetrahydrofuran / 6 h / 65 °C

3.1: potassium phtalimide / N,N-dimethyl-formamide / 3 h / 80 °C

3.2: 20 °C

With tetraphosphorus decasulfide; potassium phtalimide; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2018.02.036

upstream raw materials:

4-methoxyphenylacetamide

Refernces